LC IsoLink irm-LC/MS System

Thermo Scientific LC IsoLink is the first high sensitivity interface connecting HPLC with Isotope Ratio MS for the reproducible and accurate on-line determination of C/12C isotope ratios.

The LC IsoLink is built to directly address the analysis of polar and thermo-labile compounds.

All organic compounds eluting from an HPLC column are analyzed while maintaining the chromatographic resolution. This opens up a whole new world in the application of isotope ratio mass spectrometry.

  • Isotope ratio data on an HPLC time scale
  • Integrity of chromatographic resolution
  • High sensitivity sample analysis in the low nano-mole range
  • Accurate and reproducible results
  • Direct injection of international reference materials
  • Maintenance-free operation
  • High throughput
  • Capability for full automation

Metabolism Studies

  • Tracer experiments with amino acids, lipids, carbohydrates
  • Nucleotide analysis for DNA synthesis rates

Food and Food Ingredients

  • Authentication of honey and fruit juices
  • Determining origin of flavors and nutrients
  • Analysis of phospholipids, carbohydrates, amino acids and vitamins


  • Authenticity control of drugs
  • Investigation of agents and additives

Doping control

  • Analysis of steroids and hormones


  • History of biomolecules in sediments and soils

Recommended for: 

Metabolism studies, food and food ingredients, pharmaceuticals, doping control, biogeochemistry

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